A macroscopic description of biomolecular transport.

نویسنده

  • T C Elston
چکیده

We present a general algorithm for computing the effective diffusion coefficient of a general class of biomolecular transport processes. The method can be applied to spatially discrete and continuous processes and takes into account the effects of thermal diffusion and chemical kinetics. To provide an illustration of the algorithm, the problem of protein translocation is considered.

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Simulation of Pedestrian Dynamics with Macroscopic and Microscopic Mathematical Models

Here, we collect two parts of a research project on the pedestrian flow modeling. Rapid growth in the volume of public transport and the need for its reasonable, efficient planning have made the description and modeling of transport and pedestrian behaviors as important research topics in the past twenty years. First, we present a macroscopic model for the pedestrian flow based on continuum mec...

متن کامل

Differential geometry-based solvation and electrolyte transport models for biomolecular modeling: a review

This chapter reviews the differential geometry-based solvation and electrolyte transport for biomolecular solvation that have been developed over the past decade. A key component of these methods is the differential geometry of surfaces theory, as applied to the solvent-solute boundary. In these approaches, the solvent-solute boundary is determined by a variational principle that determines the...

متن کامل

A “v2-f Based” Macroscopic K-Ε Model for Turbulent Flow through Porous Media

In this paper a new macroscopic k-ε model is developed and validated for turbulent flow through porous media for a wide range of porosities. The morphology of porous media is simulated by a periodic array of square cylinders. In the first step, calculations based on microscopic v2 − f model are conducted using a Galerkin/Least-Squares finite element formulation, employing equalorder bilinear ve...

متن کامل

Multiphysical modelling of fluid transport through osteo-articular media.

In this study, a multiphysical description of fluid transport through osteo-articular porous media is presented. Adapted from the model of Moyne and Murad, which is intended to describe clayey materials behaviour, this multiscale modelling allows for the derivation of the macroscopic response of the tissue from microscopical information. First the model is described. At the pore scale, electroh...

متن کامل

Transport Property Estimation of Non-Uniform Porous Media

In this work a glass micromodel which its grains and pores are non-uniform in size, shape and distribution is considered as porous medium. A two-dimensional random network model of micromodel with non-uniform pores has been constructed. The non-uniformity of porous model is achieved by assigning parametric distribution functions to pores throat and pores length, which was measured using ima...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

عنوان ژورنال:
  • Journal of mathematical biology

دوره 41 3  شماره 

صفحات  -

تاریخ انتشار 2000